THE IMMUNE RESPONSE OF BOSCHVELD CHICKENS TO A NEWCASTLE DISEASE VACCINATION PROGRAM DESIGNED FOR COMMERCIAL LAYERS

THE IMMUNE RESPONSE OF BOSCHVELD CHICKENS TO A NEWCASTLE DISEASE VACCINATION PROGRAM DESIGNED FOR COMMERCIAL LAYERS

PRIDE HODZI

BLESSED MASUNDA

TONDERAI MUTIBVU

TAKUDZWA CHARAMBIRA

TAKUDZWA MAFIGU

RUMBIDZAI NHARA

This study evaluated Boschveld chicken’s antibody response to a standard Newcastle Disease (ND) vaccination program
designed for the Hyline Brown chickens. Both breeds were challenged with the LaSota vaccine at days 1, 69, 111, and 195.
The blood samples were aseptically collected from 10 randomly selected birds per breed on each vaccination day (1, 69, 111,
and 195) and 10 days after each vaccination (10 dpi). The sera were tested for anti-ND virus (NDV) antibodies using the
Haemagglutination inhibition (HI) assay. The anti-NDV antibody titers were expressed in log 2 as geometric mean ± standard
deviation. Before any vaccination, 80% of Boschveld chicken sera tested negative for anti-ND virus antibodies, significantly
higher than that of Hyline Brown chickens (40%). Hyline Brown day-old chicks had a higher antibody titer (4.95 ± 0.21)
than Boschveld day-old chicks (3.21 ± 0.43) before vaccination. The Boschveld accumulated higher antibody titers (13.98)
than the Hyline Brown breed (13.85), despite the Boschveld having lower antibody titers at day 1. The antibody titers of the
Boschveld did not change significantly (p > 0.05) after the 4th vaccination dose. For effective immune control of ND, the
vaccination program for commercial layer chickens can be optimized to suit the Boschveld chickens by reducing the frequency
of booster vaccinations. The 4th ND vaccination must be delayed until antibody titers approach the minimum protective
threshold. This intervention can also be adopted for Boschveld chicken’s close relatives, such as village (native) chickens.

Tropical Animal Health and Production

2025